Computational Neuroscience

Linked dimensions of psychopathology and connectivity in functional brain networks
Neurobiological abnormalities associated with psychiatric disorders do not map well to existing diagnostic categories. High …
Xia Cedric Huchuan, Ma Zongming, Ciric Rastko, Gu Shi, Betzel Richard F, Kaczkurkin, Antonia N, Calkins, Monica E, Cook Philip A, Garcia de la Garza Angel, Vandekar Simon N, others
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Linked dimensions of psychopathology and connectivity in functional brain networks
Benchmarking measures of network controllability on canonical graph models
The control of networked dynamical systems opens the possibility for new discoveries and therapies in systems biology and neuroscience. …
Wu-Yan Elena, Betzel Richard F, Tang Evelyn, Gu Shi, Pasqualetti Fabio, Bassett Danielle S
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Benchmarking measures of network controllability on canonical graph models
Detecting hierarchical genome folding with network modularity
Mammalian genomes are folded in a hierarchy of compartments, topologically associating domains (TADs), subTADs and looping …
Norton Heidi K, Emerson Daniel J, Huang Harvey, Kim Jesi, Titus Katelyn R, Gu Shi, Bassett Danielle S, Phillips-Cremins Jennifer E
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Detecting hierarchical genome folding with network modularity
Developmental increases in white matter network controllability support a growing diversity of brain dynamics
As the human brain develops, it increasingly supports coordinated control of neural activity. The mechanism by which white matter …
Tang Evelyn, Giusti Chad, Baum Graham L, Gu Shi, Pollock Eli, Kahn Ari E, Roalf David R, Moore Tyler M, Ruparel Kosha, Gur Ruben C, others
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Developmental increases in white matter network controllability support a growing diversity of brain dynamics
Optimal trajectories of brain state transitions
The complexity of neural dynamics stems in part from the complexity of the underlying anatomy. Yet how white matter structure …
Gu Shi, Betzel Richard F, Mattar Marcelo G, Cieslak Matthew, Delio Philip R, Grafton Scott T, Pasqualetti Fabio, Bassett Danielle S
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Optimal trajectories of brain state transitions
Stimulation-based control of dynamic brain networks
The ability to modulate brain states using targeted stimulation is increasingly being employed to treat neurological disorders and to …
Muldoon Sarah Feldt, Pasqualetti Fabio, Gu Shi, Cieslak Matthew, Grafton Scott T, Vettel Jean M, Bassett Danielle S
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Stimulation-based control of dynamic brain networks
Optimally controlling the human connectome:the role of network topology
To meet ongoing cognitive demands, the human brain must seamlessly transition from one brain state to another, in the process drawing …
Betzel Richard F, Gu Shi, Medaglia John D, Pasqualetti Fabio, Bassett Danielle S
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Optimally controlling the human connectome:the role of network topology
Controllability of structural brain networks
Cognitive function is driven by dynamic interactions between large-scale neural circuits or networks, enabling behaviour. However, …
Gu Shi, Pasqualetti Fabio, Cieslak Matthew, Telesford Qawi K, Yu Alfred B, Kahn Ari E, Medaglia John D, Vettel Jean M, Miller Michael B, Grafton Scott T, others
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Controllability of structural brain networks
Emergence of system roles in normative neurodevelopment
Adult human cognition is supported by systems of brain regions, or modules, that are functionally coherent at rest and collectively …
Gu Shi, Satterthwaite Theodore D, Medaglia John D, Yang Muzhi, Gur Raquel E, Gur Ruben C, Bassett Danielle S
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Emergence of system roles in normative neurodevelopment